====== The Type III Effector XopAO from //Xanthomonas// ======

Author: [[https://www.researchgate.net/profile/Ralf-Koebnik|Ralf Koebnik]]\\
Internal reviewer:\\
Expert reviewer: **WANTED!**

Class: XopAO\\
Family: XopAO\\
Prototype: XGA_1250 (//Xanthomonas hortorum// pv. //gardneri//, ex. //Xanthomonas gardneri//; strain 101 = ATCC 19865)\\
GenBank ID: [[https://www.ncbi.nlm.nih.gov/protein/EGD20072.1|EGD20072.1]] (206 aa)\\
RefSeq ID: [[https://www.ncbi.nlm.nih.gov/protein/WP_162267513.1|WP_162267513.1]] (207 aa)\\
3D structure: Unknown

===== Biological function =====

=== How discovered? ===

XopAO was predicted to be a type 3 effector based on homology to AvrRpm1, a type 3 effector from //Pseudomonas syringae// (Potnis //et al.//, 2011).
=== (Experimental) evidence for being a T3E ===

T3SS-mediated translocation of XopAO was assessed by constructing fusion genes with the C-terminal end of AvrBs2 coding sequence (//avrBs2// <sub>62-574</sub>) in a race 6 strain of //X. euvesicatoria//. Translocation was measured in pepper cv. ECW 20R, containing the resistance gene //Bs2//. //xopAO// was demonstrated to direct AvrBs2-specific hypersensitive reactions in ECW 20R (Potnis //et al.//, 2011).
=== Regulation ===

=== Phenotypes ===

=== Localization ===

=== Enzymatic function ===

=== Interaction partners ===

===== Conservation =====

=== In xanthomonads ===

=== In other plant pathogens/symbionts ===

===== References =====

Potnis N, Krasileva K, Chow V, Almeida NF, Patil PB, Ryan RP, Sharlach M, Behlau F, Dow JM, Momol M, White FF, Preston JF, Vinatzer BA, Koebnik R, Setubal JC, Norman DJ, Staskawicz BJ, Jones JB (2011). Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper. BMC Genomics 12: 146. DOI: [[https://doi.org/10.1186/1471-2164-12-146|10.1186/1471-2164-12-146]]