bacteria:t3e:xoph
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| bacteria:t3e:xoph [2020/07/08 17:45] – [XopH] rkoebnik | bacteria:t3e:xoph [2025/07/04 23:34] (current) – jfpothier | ||
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| - | ====== XopH ====== | + | ====== |
| - | Author: Isabel Rodrigues\\ | + | Author: |
| - | Internal reviewer: | + | Internal reviewer: |
| - | Expert reviewer: FIXME | + | |
| Class: XopH\\ | Class: XopH\\ | ||
| - | Family: XopH\\ | + | Families: XopH1, XopH2\\ |
| - | Prototype: | + | Prototype: |
| - | RefSeq | + | GenBank |
| - | Synonym: AvrBs1.1\\ | + | GenBank ID (XopH1): [[https:// |
| - | 3D structure: [[https://swissmodel.expasy.org/repository/uniprot/P0A0W1|https:// | + | RefSeq ID: XopH1 [[https://www.ncbi.nlm.nih.gov/protein/WP_011345706.1|WP_011345706.1]] (356 aa), XopH2 [[https:// |
| + | Synonym: AvrBs1.1, AvrBs7 (Potnis //et al.//, 2012)\\ | ||
| + | 3D structure: [[https:// | ||
| ===== Biological function ===== | ===== Biological function ===== | ||
| Line 16: | Line 17: | ||
| === How discovered? === | === How discovered? === | ||
| - | The XopH effector, also known as AvrBs1.1 (White //et al//., 2009), was discovered due to its virulent activity (Gurenn //et al//., 2006). Later, this effector began to be identified based on the coregulation with the TTS system (Gurenn | + | The XopH effector, also known as AvrBs1.1 (White //et al//., 2009), was first reported in 1988 (Ronald and Staskawicz 1988) and discovered due to its virulent activity (Gurenn //et al//., 2006). Later, this effector began to be identified based on the coregulation with the TTS system (Gurlebeck |
| === (Experimental) evidence for being a T3E === | === (Experimental) evidence for being a T3E === | ||
| - | The effector XopH, inhibited flg22-induced callose deposition //in planta// (Popov //et al//., 2016), dephosphorylates myo- inositol-hexakisphosphate (phytate, InsP6) //in vitro// and //in vivo// and enhanced disease symptoms (Blüher //et al//., 2017). | + | The effector XopH, inhibited flg22-induced callose deposition //in planta// (Popov //et al//., 2016), dephosphorylates myo- inositol-hexakisphosphate (phytate, InsP6) |
| === Regulation === | === Regulation === | ||
| Line 27: | Line 30: | ||
| This effector can inhibit flg22- but not ABA-inducible reporter gene activation in protoplasts act as PTI inhibitors in planta and contribute to development of disease symptoms like chlorosis (Popov //et al//., 2016). XopH liberates phosphate from the plant tissue to improve the nutritional status of the pathogen what causes the plant show obvious symptoms of phosphorus deficiency (Blüher //et al//., 2017). Transgenic //Nicotiana benthamiana// | This effector can inhibit flg22- but not ABA-inducible reporter gene activation in protoplasts act as PTI inhibitors in planta and contribute to development of disease symptoms like chlorosis (Popov //et al//., 2016). XopH liberates phosphate from the plant tissue to improve the nutritional status of the pathogen what causes the plant show obvious symptoms of phosphorus deficiency (Blüher //et al//., 2017). Transgenic //Nicotiana benthamiana// | ||
| + | |||
| === Localization === | === Localization === | ||
| The effector XopH is localized in the nucleus and in the cytoplasm of the plant cell (Popov //et al//., 2016; Blüher //et al//., 2017). | The effector XopH is localized in the nucleus and in the cytoplasm of the plant cell (Popov //et al//., 2016; Blüher //et al//., 2017). | ||
| + | |||
| === Enzymatic function === | === Enzymatic function === | ||
| XopH is a T3E with phytate-degrading activity, //in vitro// and //in planta// (Blüher //et al//., 2017). | XopH is a T3E with phytate-degrading activity, //in vitro// and //in planta// (Blüher //et al//., 2017). | ||
| + | |||
| === Interaction partners === | === Interaction partners === | ||
| Line 41: | Line 47: | ||
| === In xanthomonads === | === In xanthomonads === | ||
| - | Yes (//e.g. Xanthomonas campestris pv. campestris// | + | Yes (//e.g. Xanthomonas campestris pv. campestris// |
| === In other plant pathogens/ | === In other plant pathogens/ | ||
| Line 50: | Line 57: | ||
| Blüher D, Laha D, Thieme S, Hofer A, Eschen-Lippold L, Masch A, Balcke G, Pavlovic I, Nagel O, Schonsky A, Hinkelmann R, Wörner J, Parvin N, Greiner R, Weber S, Tissier A, Schutkowski M, Lee J, Jessen H, Schaaf G, Bonas U (2017). A 1-phytase type III effector interferes with plant hormone signaling. Nat. Commun. 8: 2159. DOI: [[http:// | Blüher D, Laha D, Thieme S, Hofer A, Eschen-Lippold L, Masch A, Balcke G, Pavlovic I, Nagel O, Schonsky A, Hinkelmann R, Wörner J, Parvin N, Greiner R, Weber S, Tissier A, Schutkowski M, Lee J, Jessen H, Schaaf G, Bonas U (2017). A 1-phytase type III effector interferes with plant hormone signaling. Nat. Commun. 8: 2159. DOI: [[http:// | ||
| - | Gurenn | + | Gurlebeck |
| + | |||
| + | Hajri A, Pothier JF, Fischer-Le Saux M, Bonneau S, Poussier S, Boureau T, Duffy B, Manceau C (2011). Type three effector gene distribution and sequence analysis provide new insights into the pathogenicity of plant-pathogenic // | ||
| Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple // | Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple // | ||
| - | Potnis N, Minsavage G, Smith J K, Hurlbert J C, Norman D, Rodrigues R, Stall R E, Jones JB (2012). Avirulence proteins AvrBs7 from // | + | Potnis N, Minsavage G, Smith J K, Hurlbert J C, Norman D, Rodrigues R, Stall R E, Jones JB (2012). Avirulence proteins AvrBs7 from // |
| - | White FF, Potnis N, Jones JB, Koebnik R (2009). The type III effectors of // | + | Ronald PC, Staskawicz BJ (1988). The avirulence gene //avrBs1// from // |
| + | |||
| + | White FF, Potnis N, Jones JB, Koebnik R (2009). The type III effectors of // | ||
| + | |||
| + | White FF, Jones JB (2018). One effector at a time. Nature Plants 4: 134-135. DOI: [[https:// | ||
| ===== Further reading ===== | ===== Further reading ===== | ||
| - | Thieme F (2006). Genombasierte Identifizierung neuer potentieller Virulenzfaktoren von // | + | Thieme F (2006). Genombasierte Identifizierung neuer potentieller Virulenzfaktoren von // |
| Thieme F, Koebnik R, Bekel T, Berger C, Boch J, Büttner D, Caldana C, Gaigalat L, Goesmann A, Kay S, Kirchner O, Lanz C, Linke B, McHardy AC, Meyer F, Mittenhuber G, Nies DH, Niesbach-Klösgen U, Patschkowski T, Rückert C, Rupp O, Schneiker S, Schuster SC, Vorhölter FJ, Weber E, Pühler A, Bonas U, Bartels D, Kaiser O (2005). Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium // | Thieme F, Koebnik R, Bekel T, Berger C, Boch J, Büttner D, Caldana C, Gaigalat L, Goesmann A, Kay S, Kirchner O, Lanz C, Linke B, McHardy AC, Meyer F, Mittenhuber G, Nies DH, Niesbach-Klösgen U, Patschkowski T, Rückert C, Rupp O, Schneiker S, Schuster SC, Vorhölter FJ, Weber E, Pühler A, Bonas U, Bartels D, Kaiser O (2005). Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium // | ||
| + | |||
| + | ===== Acknowledgements ===== | ||
| + | |||
| + | This fact sheet is based upon work from COST Action CA16107 EuroXanth, supported by COST (European Cooperation in Science and Technology). | ||
bacteria/t3e/xoph.1594226754.txt.gz · Last modified: 2023/01/09 10:20 (external edit)
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