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bacteria:t3e:xope4

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bacteria:t3e:xope4 [2025/02/12 23:56] jfpothierbacteria:t3e:xope4 [2025/07/24 22:28] (current) jfpothier
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 Author: [[https://www.researchgate.net/profile/Jaime_Cubero|Jaime Cubero]]\\ Author: [[https://www.researchgate.net/profile/Jaime_Cubero|Jaime Cubero]]\\
 Internal reviewer: [[https://www.researchgate.net/profile/Eran_Bosis|Eran Bosis]]\\ Internal reviewer: [[https://www.researchgate.net/profile/Eran_Bosis|Eran Bosis]]\\
-Expert reviewer: [[https://www.researchgate.net/profile/Adriana_Bernal|Adriana Bernal]]+Expert reviewer: [[https://www.researchgate.net/profile/Adriana_Bernal|Adriana Bernal]]\\
  
 Class: XopE\\ Class: XopE\\
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 XopE4 was first identified by sequence homology searches (Moreira //et al//., 2010). XopE4 was first identified by sequence homology searches (Moreira //et al//., 2010).
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 === (Experimental) evidence for being a T3E === === (Experimental) evidence for being a T3E ===
  
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 The gene sequence of xopE4 is similar to XopE2 (avrXacE3), but due to its low amino acid sequence identity (31%) was considered a different effector that can discriminate between X. citri and //X. fuscans// pv. aurantifolii strains, both causing citrus bacterial canker (Moreira //et al//., 2010; Dalio //et al//., 2017). Disease symptoms caused by //Xanthomonas axonopodis// pv. //manihotis// mutant strains deleted for //xopE4// are similar to those caused by the wild-type strain. Moreover, using heterologous systems XopE4 was unable to suppress (PAMP)-triggered immunity (PTI) but showed weak ability to suppress effector-triggered immunity (ETI) (Medina //et al//., 2018). The gene sequence of xopE4 is similar to XopE2 (avrXacE3), but due to its low amino acid sequence identity (31%) was considered a different effector that can discriminate between X. citri and //X. fuscans// pv. aurantifolii strains, both causing citrus bacterial canker (Moreira //et al//., 2010; Dalio //et al//., 2017). Disease symptoms caused by //Xanthomonas axonopodis// pv. //manihotis// mutant strains deleted for //xopE4// are similar to those caused by the wild-type strain. Moreover, using heterologous systems XopE4 was unable to suppress (PAMP)-triggered immunity (PTI) but showed weak ability to suppress effector-triggered immunity (ETI) (Medina //et al//., 2018).
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 === Localization === === Localization ===
  
 As XopE4 does not have a predicted myristoylation site, suggesting that it may not be targeted to the cell membrane as the other XopE family member (Moreira //et al//., 2010). As XopE4 does not have a predicted myristoylation site, suggesting that it may not be targeted to the cell membrane as the other XopE family member (Moreira //et al//., 2010).
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 === Enzymatic function === === Enzymatic function ===
  
 XopE4 belongs to the HopX effector family, which are part of the transglutaminase superfamily (Nichmuk //et al//., 2007). XopE4 belongs to the HopX effector family, which are part of the transglutaminase superfamily (Nichmuk //et al//., 2007).
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 === Interaction partners === === Interaction partners ===
  
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 Yes (//e.g.//, //X. axonopodis//). Yes (//e.g.//, //X. axonopodis//).
  
-XopE4 is also present in //X. fragariae // (Vandroemme //et al//., 2013) and it is not very conserved among //X. perforans// strains (Schwartz //et al//., 2015).+XopE4 is also present in //X. fragariae// (Vandroemme //et al//., 2013) and it is not very conserved among //X. perforans// strains (Schwartz //et al//., 2015).
 === In other plant pathogens/symbionts === === In other plant pathogens/symbionts ===
  
bacteria/t3e/xope4.1739404595.txt.gz · Last modified: 2025/02/12 23:56 by jfpothier