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bacteria:t3e:xope3

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bacteria:t3e:xope3 [2025/01/27 22:49] – [Biological function] jfpothierbacteria:t3e:xope3 [2025/02/12 23:55] (current) jfpothier
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 GenBank ID: [[https://www.ncbi.nlm.nih.gov/protein/AAM38068.1|AAM38068.1]] (356 aa)\\ GenBank ID: [[https://www.ncbi.nlm.nih.gov/protein/AAM38068.1|AAM38068.1]] (356 aa)\\
 RefSeq ID: [[https://www.ncbi.nlm.nih.gov/protein/WP_011052114.1|WP_011052114.1]] (356 aa)\\ RefSeq ID: [[https://www.ncbi.nlm.nih.gov/protein/WP_011052114.1|WP_011052114.1]] (356 aa)\\
-Synonym: AvrXacE2 (//Xanthomonas citri //pv. //citri//)\\+Synonym: AvrXacE2 (//Xanthomonas citri// pv. //citri//)\\
 3D structure: Contains a catalytic triad of cysteine, histidine and aspartic acid, and have been grouped with peptide N-glycanases (PNGases, members of the transglutaminase protein superfamily). XopE3 contains N-myristoylation motifs (Dunger //et al//., 2012). 3D structure: Contains a catalytic triad of cysteine, histidine and aspartic acid, and have been grouped with peptide N-glycanases (PNGases, members of the transglutaminase protein superfamily). XopE3 contains N-myristoylation motifs (Dunger //et al//., 2012).
 ===== Biological function ===== ===== Biological function =====
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 === Interaction partners === === Interaction partners ===
  
-In //X. citri// subsp. //citri// A306 the gene coding for XopE3 is in a region hypothesized to be a genomic island (Moreira //et al.//, 2010). This region or parts of it are conserved in many //Xanthomonas// strains, as shown by a genomic neighborhood search in the Integrated Microbial Genomes platform. In particular, in this search gene XAC3225 is nearly always adjacent to XAC3224 (//xopE3//), suggesting that the protein coded by XAC3225 is an interaction partner of XopE3. Moreira //et al.// (2010) commented on this as follows: "Next to //xopE3// (XAC3224) we find gene XAC3225, whose product is annotated as tranglycosylase //mltB//. This gene has strong similarity (e-value 10<sup>-133</sup>  , 100% coverage) to //hopAJ1// from //P. syringae// pv. //tomato// strain DC3000, where it is annotated as a T3SS helper protein. Although the //hopAJ1// gene is not itself a T3SS substrate, it contributes to effector translocation (Oh //et al.//, 2007). A mutant with a deletion of XAC3225 has reduced ability to cause canker (mutant phenotypes include a reduction in water soaking, hyperplasia, and necrosis compared to wild type) (Laia //et al.//, 2009)".+In //X. citri// subsp. //citri// A306 the gene coding for XopE3 is in a region hypothesized to be a genomic island (Moreira //et al.//, 2010). This region or parts of it are conserved in many //Xanthomonas// strains, as shown by a genomic neighborhood search in the Integrated Microbial Genomes platform. In particular, in this search gene XAC3225 is nearly always adjacent to XAC3224 (//xopE3//), suggesting that the protein coded by XAC3225 is an interaction partner of XopE3. Moreira //et al.// (2010) commented on this as follows: "Next to //xopE3// (XAC3224) we find gene XAC3225, whose product is annotated as tranglycosylase //mltB//. This gene has strong similarity (e-value 10<sup>-133</sup>, 100% coverage) to //hopAJ1// from //P. syringae// pv. //tomato// strain DC3000, where it is annotated as a T3SS helper protein. Although the //hopAJ1// gene is not itself a T3SS substrate, it contributes to effector translocation (Oh //et al.//, 2007). A mutant with a deletion of XAC3225 has reduced ability to cause canker (mutant phenotypes include a reduction in water soaking, hyperplasia, and necrosis compared to wild type) (Laia //et al.//, 2009)".
 ===== Conservation ===== ===== Conservation =====
  
bacteria/t3e/xope3.1738018153.txt.gz · Last modified: 2025/01/27 22:49 by jfpothier