bacteria:t3e:xopba
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| bacteria:t3e:xopba [2023/05/26 19:07] – [XopBA] rkoebnik | bacteria:t3e:xopba [2024/12/16 14:51] (current) – [The Type III Effector XopBA from //Xanthomonas//] rkoebnik | ||
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| - | ====== XopBA ====== | + | ====== |
| - | Author: [[https:// | + | Author: [[https:// |
| - | Internal reviewer: | + | |
| - | Expert reviewer: | + | |
| Class: XopBA\\ | Class: XopBA\\ | ||
| Line 15: | Line 13: | ||
| === How discovered? === | === How discovered? === | ||
| - | XopAU was discovered by homology to HopW/ | + | XopBA was discovered by homology to HopW/ |
| === (Experimental) evidence for being a T3E === | === (Experimental) evidence for being a T3E === | ||
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| === Phenotypes === | === Phenotypes === | ||
| - | Ectopic expression of the distant homolog in //E. coli//, EspW, results in formation of unique membrane protrusions (Sandu et al., 2017) | + | Ectopic expression of the distant homolog in //E. coli//, EspW, results in formation of unique membrane protrusions (Sandu |
| === Localization === | === Localization === | ||
| - | The distant homolog in //E. coli//, EspW, and Kif15 colocalized in cotransfected cells, while ectopically expressed Kif15 localized to the actin pedestals following EHEC infection (Sandu et al., 2017). | + | The distant homolog in //E. coli//, EspW, and Kif15 colocalized in cotransfected cells, while ectopically expressed Kif15 localized to the actin pedestals following EHEC infection (Sandu |
| === Enzymatic function === | === Enzymatic function === | ||
| - | The distant homolog in //E. coli//, EspW, modulates actin dynamics in a Rac1-dependent manner (Sandu et al., 2017). | + | The distant homolog in //E. coli//, EspW, modulates actin dynamics in a Rac1-dependent manner (Sandu |
| === Interaction partners === | === Interaction partners === | ||
| - | The distant homolog in //E. coli//, EspW, was found to interact with the motor protein Kif15 in a yeast two-hybrid screen (Sandu et al., 2017). | + | The distant homolog in //E. coli//, EspW, was found to interact with the motor protein Kif15 in a yeast two-hybrid screen (Sandu |
| ===== Conservation ===== | ===== Conservation ===== | ||
bacteria/t3e/xopba.1685124432.txt.gz · Last modified: 2023/05/26 19:07 by rkoebnik
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