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====== The Type III Effector XopAX from //Xanthomonas// ======

Author: [[https://www.researchgate.net/profile/Doron_Teper|Doron Teper]]

Class: XopAX\\
Family: XopAX\\
Prototype: XCVd0086 (//Xanthomonas euvesicatoria// pv. //euvesicatoria//, ex //Xanthomonas campestris// pv. //vesicatoria//; strain 85-10)\\
GenBank ID: [[https://www.ncbi.nlm.nih.gov/protein/CAJ19898.1|CAJ19898.1]] (383 aa)\\
RefSeq ID: [[https://www.ncbi.nlm.nih.gov/protein/WP_041854960.1|WP_041854960.1]] (353 aa)\\
3D structure: Unknown

===== Biological function =====

=== How discovered? ===

XopAX (XCVd0086 in //X. euvesicatoria// strain 85-10; GenBank [[https://www.ncbi.nlm.nih.gov/protein/78033899|CAJ19898]]) was discovered using a machine-learning approach (Teper //et al//., 2016).
=== (Experimental) evidence for being a T3E ===

XopAX fused to the AvrBs2 reporter was shown to translocate into plant cells in an //hrpF//-dependent manner (Teper //et al//., 2016).
=== Regulation ===

Unknown.

=== Phenotypes ===

Unknown.

=== Localization ===

Unknown.

=== Enzymatic function ===

Unknown.

=== Interaction partners ===

Unknown.

===== Conservation =====

=== In xanthomonads ===

Yes (//X. euvevsicatoria//, //X. campestris// pv. //campestris//, //X. arboricola//).
=== In other plant pathogens/symbionts ===

Yes (//Pseudomonas syringae// pv. //aceris//).
===== References =====

Teper D, Burstein D, Salomon D, Gershovitz M, Pupko T, Sessa G (2016). Identification of novel //Xanthomonas euvesicatoria// type III effector proteins by a machine-learning approach. Mol. Plant Pathol. 17: 398-411. DOI: [[https://doi.org/10.1111/mpp.12288|10.1111/mpp.12288]]

===== Acknowledgements =====

This fact sheet is based upon work from COST Action CA16107 EuroXanth, supported by COST (European Cooperation in Science and Technology).
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