Authors: Daiva Burokiene, Edyta Dermic, Dagmar Stehlikova, Mariya Stoyanova, Ralf Koebnik
Internal reviewer:
Expert reviewer:

Class: XopAJ
Family: XopAJ
Prototype: XopAJ aka AvrRxo1 (Xanthomonas oryzae pv. oryzicola; strain BLS256)
RefSeq ID: WP_014504815.1 (421 aa)
3D structure: 4Z8T, 4Z8Q, 4Z8U, 4Z8U – e.g. 4Z8T

Yes (e.g. X. alfalfae, X. axonopodis, X. bromi, X. euvesicatoria, X. oryzae, X. translucens)

Yes (Acidovorax spp.)

Bahadur RP, Basak J (2014). Molecular modeling of protein-protein interaction to decipher the structural mechanism of nonhost resistance in rice. J. Biomol. Struct. Dyn. 32(4): 669-681. DOI: 10.1080/07391102.2013.787370.

Han Q, Zhou C, Wu S, Liu Y, Triplett L, Miao J, Tokuhisa J, Deblais L, Robinson H, Leach JE, Li J, Zhao B (2015). Crystal structure of Xanthomonas AvrRxo1-ORF1, a type III effector with a polynucleotide kinase domain, and its interactor AvrRxo1-ORF2. Structure 23(10): 1900-1909. DOI: 10.1016/j.str.2015.06.030.

Ji ZY, Xiong L, Zou LF, Li YR, Ma WX, Liu L, Zakria M, Ji GH, Chen GY (2014). AvrXa7-Xa7 mediated defense in rice can be suppressed by transcriptional activator-like effectors TAL6 and TAL11a from Xanthomonas oryzae pv. oryzicola. Mol. Plant Microbe Interact. 27(9): 983-995. DOI: 10.1094/MPMI-09-13-0279-R. Retraction in: Mol Plant Microbe Interact. (2014-Dec) 27(12): 1413.

Liu H, Chang Q, Feng W, Zhang B, Wu T, Li N, Yao F, Ding X, Chu Z (2014). Domain dissection of AvrRxo1 for suppressor, avirulence and cytotoxicity functions. PLoS One 9(12): e113875. DOI: 10.1371/journal.pone.0113875.

Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple Xanthomonas euvesicatoria type III effectors inhibit flg22-triggered immunity. Mol. Plant Microbe Interact. 29(8): 651-660. DOI: 10.1094/MPMI-07-16-0137-R.

Salomon D, Dar D, Sreeramulu S, Sessa G (2011). Expression of Xanthomonas campestris pv. vesicatoria type III effectors in yeast affects cell growth and viability. Mol. Plant Microbe Interact. 24(3): 305-314. DOI: 10.1094/MPMI-09-10-0196.

Schuebel F, Rocker A, Edelmann D, Schessner J, Brieke C, Meinhart A (2016). 3'-NADP and 3'-NAADP, two metabolites formed by the bacterial type III effector AvrRxo1. J. Biol. Chem. 291(44): 22868-22880. DOI: 10.1074/jbc.M116.751297.

Shidore T, Broeckling CD, Kirkwood JS, Long JJ, Miao J, Zhao B, Leach JE, Triplett LR (2017). The effector AvrRxo1 phosphorylates NAD in planta. PLoS Pathog. 13(6): e1006442. DOI: 10.1371/journal.ppat.1006442.

Triplett LR, Shidore T, Long J, Miao J, Wu S, Han Q, Zhou C, Ishihara H, Li J, Zhao B, Leach JE (2016). AvrRxo1 Is a bifunctional type III secreted effector and toxin-antitoxin system component with homologs in diverse environmental contexts. PLoS One 11(7): e0158856. DOI: 10.1371/journal.pone.0158856.

Wonni I, Cottyn B, Detemmerman L, Dao S, Ouedraogo L, Sarra S, Tekete C, Poussier S, Corral R, Triplett L, Koita O, Koebnik R, Leach J, Szurek B, Maes M, Verdier V (2014). Analysis of Xanthomonas oryzae pv. oryzicola population in Mali and Burkina Faso reveals a high level of genetic and pathogenic diversity. Phytopathology 104(5): 520-531. DOI: 10.1094/PHYTO-07-13-0213-R.

Xie XW, Yu J, Xu JL, Zhou YL, Li ZK (2007). Introduction of a non-host gene Rxo1 cloned from maize resistant to rice bacterial leaf streak into rice varieties. Sheng Wu Gong Cheng Xue Bao 23(4): 607-611. DOI: 10.1016/S1872-2075(07)60039-9.

Zhao B, Ardales EY, Raymundo A, Bai J, Trick HN, Leach JE, Hulbert SH (2004). The avrRxo1 gene from the rice pathogen Xanthomonas oryzae pv. oryzicola confers a nonhost defense reaction on maize with resistance gene Rxo1. Mol. Plant-Microbe Interact. 17(7): 771-779. DOI: 10.1094/MPMI.2004.17.7.771.

Zhao B, Lin X, Poland J, Trick H, Leach J, Hulbert S (2005). A maize resistance gene functions against bacterial streak disease in rice. Proc. Natl. Acad. Sci. USA. 102(43): 15383-15388. DOI: 10.1073/pnas.0503023102.