EuroXanth DokuWiki

User Tools

Site Tools

Trace: • xopab
bacteria:t3e:xopai

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
Next revision		Previous revision
bacteria:t3e:xopai [2025/02/12 23:26] – jfpothierbacteria:t3e:xopai [2025/07/13 23:25] (current) – jfpothier
Line 1: Line 1:
 ====== The Type III Effector XopAI from //Xanthomonas// ====== ====== The Type III Effector XopAI from //Xanthomonas// ======
  
-Author: [[https://www.researchgate.net/profile/Ralf-Koebnik|Ralf Koebnik]]+Author: [[https://www.researchgate.net/profile/Ralf-Koebnik|Ralf Koebnik]]\\
  
 Class: XopAI\\ Class: XopAI\\
Line 19: Line 19:
  
 Based on homology to effectors from //Pseudomonas syringae// and a strongly conserved 43‐amino‐acid N‐terminal domain that is also found in the N‐termini of effectors in class XopE and XopJ, XopAI was proposed to be a T3E (Stavrinides //et al.//, 2006; White //et al.//, 2009). Based on homology to effectors from //Pseudomonas syringae// and a strongly conserved 43‐amino‐acid N‐terminal domain that is also found in the N‐termini of effectors in class XopE and XopJ, XopAI was proposed to be a T3E (Stavrinides //et al.//, 2006; White //et al.//, 2009).
 +
 === (Experimental) evidence for being a T3E === === (Experimental) evidence for being a T3E ===
  
Line 26: Line 27:
  
 Using microarrays, seven T3E genes from //X. citri// pv. //citri// were found to be upregulated in planta, five of which in all the three times investigated, i.e. 24 hpi, 72 hpi and 120 hpi (//xopE1//, //xopN//, //xopK//, //xopE3//, //xopAI//), and the two remaining at the later times of the infectious process (//xopE2// and //xopV//) (de Laia //et al.//, 2019). Using microarrays, seven T3E genes from //X. citri// pv. //citri// were found to be upregulated in planta, five of which in all the three times investigated, i.e. 24 hpi, 72 hpi and 120 hpi (//xopE1//, //xopN//, //xopK//, //xopE3//, //xopAI//), and the two remaining at the later times of the infectious process (//xopE2// and //xopV//) (de Laia //et al.//, 2019).
 +
 === Phenotypes === === Phenotypes ===
  
Line 33: Line 35:
  
 The XopAI N‐terminal domain contains a myristoylation motif, which was previously identified in several T3Es of //P. syringae//, indicating that effectors with this N‐terminal domain are targeted to host cellular membranes (White //et al.//, 2009). The XopAI N‐terminal domain contains a myristoylation motif, which was previously identified in several T3Es of //P. syringae//, indicating that effectors with this N‐terminal domain are targeted to host cellular membranes (White //et al.//, 2009).
 +
 === Enzymatic function === === Enzymatic function ===
  
Line 40: Line 43:
  
 Structural homologs of XopAI are, among others, the HopU1 (//Pseudomonas syringae// T3SS-secreted effector HopU1, PDB code [[https://www.rcsb.org/structure/3U0J|3U0J]]), Tre1 (//Serratia proteamaculans// T6SS-secreted ADP-ribosyltransferase effector 1, PDB code [[https://www.rcsb.org/structure/6DRH|6DRH]]), ART2.2 (rat mART2.2, PDB code [[https://www.rcsb.org/structure/1GXY|1GXY]]), and ExoS (//Pseudomonas// //aeruginosa// exoenzyme S, PDB code [[https://www.rcsb.org/structure/6GN8|6GN8]]) (Liu //et al.//, 2019). Structural homologs of XopAI are, among others, the HopU1 (//Pseudomonas syringae// T3SS-secreted effector HopU1, PDB code [[https://www.rcsb.org/structure/3U0J|3U0J]]), Tre1 (//Serratia proteamaculans// T6SS-secreted ADP-ribosyltransferase effector 1, PDB code [[https://www.rcsb.org/structure/6DRH|6DRH]]), ART2.2 (rat mART2.2, PDB code [[https://www.rcsb.org/structure/1GXY|1GXY]]), and ExoS (//Pseudomonas// //aeruginosa// exoenzyme S, PDB code [[https://www.rcsb.org/structure/6GN8|6GN8]]) (Liu //et al.//, 2019).
 +
 === Interaction partners === === Interaction partners ===
  
Line 49: Line 53:
  
 XopAI homologs were also found in //X. citri// pv. //bilvae// and //X. citri// pv. //glycines//, as well as in the species //X. arboricola//, //X. hortorum//, //X. vesicatoria// (Moreira //et al.//, 2010; Liu //et al.//, 2019). XopAI homologs were also found in //X. citri// pv. //bilvae// and //X. citri// pv. //glycines//, as well as in the species //X. arboricola//, //X. hortorum//, //X. vesicatoria// (Moreira //et al.//, 2010; Liu //et al.//, 2019).
 +
 === In other plant pathogens/symbionts === === In other plant pathogens/symbionts ===
  
Line 75: Line 80:
  
 White FF, Potnis N, Jones JB, Koebnik R (2009). The type III effectors of //Xanthomonas//. Mol. Plant Pathol. 10: 749-766. DOI: [[https://doi.org/10.1111/j.1364-3703.2009.00590.x|10.1111/j.1364-3703.2009.00590.x]] White FF, Potnis N, Jones JB, Koebnik R (2009). The type III effectors of //Xanthomonas//. Mol. Plant Pathol. 10: 749-766. DOI: [[https://doi.org/10.1111/j.1364-3703.2009.00590.x|10.1111/j.1364-3703.2009.00590.x]]
 +
 +===== Acknowledgements =====
 +
 +This fact sheet is based upon work from COST Action CA16107 EuroXanth, supported by COST (European Cooperation in Science and Technology).
 +
  
bacteria/t3e/xopai.1739402814.txt.gz · Last modified: 2025/02/12 23:26 by jfpothier

Page Tools

Except where otherwise noted, content on this wiki is licensed under the following license: CC Attribution-Share Alike 4.0 International
CC Attribution-Share Alike 4.0 International Donate Powered by PHP Valid HTML5 Valid CSS Driven by DokuWiki