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--- bacteria:t3e:xopae [2025/07/04 23:10] – jfpothier
+++ bacteria:t3e:xopae [2025/07/24 22:24] (current) – jfpothier
@@ Line 32: / Line 32: @@
 === Phenotypes ===
-XopAE<sub>//Xee//85-10</sub> is a suppressor of PTI that was shown to inhibit flg22-mediated signaling in //Arabidopsis// and tomato protoplasts, downstream or in parallel to the activation of the MPK3 and MPK6 MAP kinases. //Pseudomonas syringae//-mediated delivery of XopAE<sub>//Xee//85-10</sub> in plants inhibits PTI-associated callose deposition at the cell wall and enhances disease symptoms in tomato (Popov //et al.//, 2016). Later, XopAE<sub>//Xpm// </sub> was confirmed to suppress basal defenses such as callose deposition and the production of reactive oxygen species (Gomez De la Cruz //et al.//, 2025).
+XopAE<sub>//Xee//85-10</sub> is a suppressor of PTI that was shown to inhibit flg22-mediated signaling in //Arabidopsis// and tomato protoplasts, downstream or in parallel to the activation of the MPK3 and MPK6 MAP kinases. //Pseudomonas syringae//-mediated delivery of XopAE<sub>//Xee//85-10</sub> in plants inhibits PTI-associated callose deposition at the cell wall and enhances disease symptoms in tomato (Popov //et al.//, 2016). Later, XopAE<sub>//Xpm//</sub> was confirmed to suppress basal defenses such as callose deposition and the production of reactive oxygen species (Gomez De la Cruz //et al.//, 2025).
 === Localization ===
-XopAE<sub>//Xee//85-10</sub>-YFP fusion protein localizes to the cytoplasm and nucleus of //Nicotiana benthamiana// leaf epidermal cells (Popov //et al.//, 2016). XopAE<sub>//Xpm// </sub> localizes to the nucleus and in scattered points throughout the cell border, while Mep23-1 shows a nucleocytoplasmic localization. Upon interaction, XopAE//<sub>Xpm</sub> // hijacks Mep23-1 to the scattered points throughout the cell border and they also interact in nucleus (Gomez De la Cruz //et al.//, 2025).
+XopAE<sub>//Xee//85-10</sub>-YFP fusion protein localizes to the cytoplasm and nucleus of //Nicotiana benthamiana// leaf epidermal cells (Popov //et al.//, 2016). XopAE<sub>//Xpm//</sub> localizes to the nucleus and in scattered points throughout the cell border, while Mep23-1 shows a nucleocytoplasmic localization. Upon interaction, XopAE//<sub>Xpm</sub> // hijacks Mep23-1 to the scattered points throughout the cell border and they also interact in nucleus (Gomez De la Cruz //et al.//, 2025).
 === Enzymatic function ===
@@ Line 44: / Line 44: @@
 === Interaction partners ===
-XopAE<sub>//Xpm// </sub> targets a small heat shock protein (Mep23-1 cochaperone) in cassava and its homolog Atp23-1 in //Arabidopsis// (Gomez De la Cruz //et al.//, 2025).
+XopAE<sub>//Xpm//</sub> targets a small heat shock protein (Mep23-1 cochaperone) in cassava and its homolog Atp23-1 in //Arabidopsis// (Gomez De la Cruz //et al.//, 2025).
 ===== Conservation =====
@@ Line 58: / Line 58: @@
 ===== References =====
-Gomez De la Cruz D, Castillo DA, Trujillo B CA, Medina CA, Hurtado V, Gil J, Padmanabhan M, Restrepo S, Dinesh-Kumar SP, Germain H, Lopez C, Bernal A (2025). XopAE effector from Xanthomonas phaseoli pv. manihotis targets HSP20-like p23 cochaperone to suppress plant basal immunity. Mol. Plant Microbe Interact., in press. DOI: [[https://doi.org/10.1094/MPMI-08-24-0086-R|10.1094/MPMI-08-24-0086-R]]
+Gomez De la Cruz D, Castillo DA, Trujillo B CA, Medina CA, Hurtado V, Gil J, Padmanabhan M, Restrepo S, Dinesh-Kumar SP, Germain H, Lopez C, Bernal A (2025). XopAE effector from //Xanthomonas phaseoli// pv. //manihotis// targets HSP20-like p23 cochaperone to suppress plant basal immunity. Mol. Plant Microbe Interact.
+: 365-375 . DOI: [[https://doi.org/10.1094/MPMI-08-24-0086-R|10.1094/MPMI-08-24-0086-R]]
 Kim JG, Park BK, Yoo CH, Jeon E, Oh J, Hwang I (2003). Characterization of the //Xanthomonas axonopodis// pv. //glycines// Hrp pathogenicity island. J. Bacteriol. 185: 3155‐3166. DOI: [[https://doi.org/10.1128/jb.185.10.3155-3166.2003|jb.185.10.3155-3166.2003]]

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